Demographic, Clinical and Genetic Features of the Patients with Familial Mediterranean Fever

Aim: This study aims to analyze the demographic, clinical and genetic features ofthe patients with familial Mediterranean fever (FMF). Material and Method: A total of 150 patients (96 men and 54 women) with FMF were included to this study. Demographic characteristics, clinical findings, and genotypic features of the patients were statistically evaluated. Results: Percentages of male and female subjects were64% and36%, respectively.The most common clinical finding in both sexeswasabdominal pain. Amyloidosis was determined in 3patients (2%), and all of them were men. The most common mutation observed in thepatients was M694V (n=153, 51%). Mutation analyseswere negative in 7 (4.6%) patients. M694V/M694Vwas the most common genotype.In the patients with homozygous M694V mutation, amyloidosis (