Evaluation of Subclinical Inflammation withNeutrophil Lymphocyte Ratio In Heavy Metal Exposure
Author(s) -
Ceylan Bal,
Uğur Nadir Karakulak,
Meşide Gündüzöz,
Müjgan Ercan,
Engın Tutkun,
Ömer Yılmaz
Publication year - 2016
Publication title -
the annals of clinical and analytical medicine
Language(s) - English
Resource type - Journals
ISSN - 2667-663X
DOI - 10.4328/jcam.4393
Subject(s) - medicine , subclinical infection , inflammation , immunology , lymphocyte , neutrophil to lymphocyte ratio , pathology
Aim: Neutrophil lymphocyte ratio (NLR) is being used frequently as a marker of subclinical inflammation. The objective of this study is to investigate the association between NLR levels and heavy metal levels in workers with lead exposure. Material and Method: Demographic and laboratory data of 1820 individuals with lead exposure were evaluated retrospectively. C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and complete blood count (CBC) were evaluated as inflammatory markers. Participants were categorized into 3 groups according to blood lead levels as < 10 %u03BCg/dL (Group 1), 10-30 %u03BCg/dL (Group 2), and > 30 %u03BCg/dL(Group 3). The association between NLR and lead was evaluated by inter-group and correlation analysis. Results: Median NLR values of Group 1, Group 2 and Group 3 were 1.45 (0.41-1.97), 1.92 (1.19-1.42), and 1,96 (1.19-7.55) respectively (
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