Liver Function Tests as Probable Markers of Preeclampsia – A Prospective Study Conducted in Riyadh

Aim: Preeclampsia is characterized by development of high blood pressure and proteinuria. It affects 5%u20138% of all pregnancies and is a major contributor to maternal and fetal morbidity and mortality. There is no single test that fulfills all the criteria for a good predictor of preeclampsia and associated hepatic dysfunction. The present study was therefore undertaken to assess the role of liver enzymes as marker in prediction of preeclampsia. Material and Method: The study comprised of 120 pregnant women divided into three groups: normal pregnant women, women with high risk of preeclampsia and women with preeclampsia. Serum levels of AST, ALT, ALP and LDH were analyzed and comparison of clinical characteristics and biochemical parameters of cases with control was performed by t-test followed by one way ANOVA. Results: There was significant increase (