The Evaluation of Solid Phase Gastric Emptying in Patients with Behcet’s Disease
Author(s) -
Asena Doğramacı,
Hülya Yalçın,
Didem Didar Balcı,
Edip Uçar,
Julide Zehra,
Ebuzer Kalender,
Asena Çiğdem Doğramacı,
Mustafa Kemal,
Mide Yarı Boşalma Zamanları,
Behçet Hastalığı,
Mide
Publication year - 2014
Publication title -
the annals of clinical and analytical medicine
Language(s) - English
Resource type - Journals
ISSN - 2667-663X
DOI - 10.4328/jcam.2115
Subject(s) - medicine , behcet's disease , gastric emptying , disease , phase (matter) , gastroenterology , intensive care medicine , stomach , chemistry , organic chemistry
Aim: Behcet%u2019s disease is a multisystemic disease that includes the mucocutaneous, ocular, cardiovascular, renal, pulmonary, joint and central nervous system involvement. Gastrointestinal system involvement is rare in Behcet%u2019s disease. Current study was planned to investigate the rate of gastric emptying in patients with Behcet%u2019s disease by using gastric emptying scintigraphy. Material and Method: In order to determine gastric emptying rate of solids, 14 patients with Behcet%u2019s disease and 14 healthy controls were studied scintigraphically. After an overnight fast, all subjects ingested a Tc- 99m DTPA labeled solid meal consisted of an egg and toasted white bread. Immediately after ingestion of the meal, subjects were positioned supine under the gamma camera and serial images were recorded continuously for 90 minutes. Half empyting time (t 1/2) and percentage of radioactive material remaining in the stomach at 60 min. were calculated. Results: The mean ages of Behcet%u2019s patients was 41.00±10.25 years and 40.57±10.05 years in control group. T ½ of Behcet%u2019s patients was found 85± 61 min. and 63±22 min. in control cases (p=0.122). Percentage of radioactive material remaining in the stomach at 60 min. was 69.3± 14.0 % and 54.6± 22.0 % in Behcet%u2019s patients and controls, respectively (p=0.035). Discussion: Although there was not a significant difference between half gastric emptying times, we determined that percentage of radioactive material remaining in the stomach at 60 min. was significantly greater in Behcet%u2019s patients than that in controls. As a result, gastric stasis could be seen in Behcet%u2019s patients due to multisystemic involvement
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom