The Role of Endocrine and Endometrial Factors in Cases of Recurrent Miscarriage: A Tertiary Center Experience | Zendy

Ahmet Uysal | Zendy; Cüneyt Taner | Zendy; Semih Mun | Zendy; Emine Çoşar | Zendy

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The Role of Endocrine and Endometrial Factors in Cases of Recurrent Miscarriage: A Tertiary Center Experience

Author(s) -

Ahmet Uysal,

Cüneyt Taner,

Semih Mun,

Emine Çoşar

Publication year - 2014

Publication title -

the annals of clinical and analytical medicine

Language(s) - English

Resource type - Journals

ISSN - 2667-663X

DOI - 10.4328/jcam.1996

Subject(s) - medicine , miscarriage , endocrine system , center (category theory) , tertiary care , gynecology , recurrent miscarriage , obstetrics , general surgery , pregnancy , hormone , chemistry , genetics , biology , crystallography

Aim: To investigate endocrinologic and endometrial factors in cases of recurrent abortions. Material and Method: In cases of recurrent abortions, clinical and ultrasonographic features, genetic, anatomic and immunologic factors, hormonal profiles and endometrial samplings were assessed. Chromosomal abnormalities and uterine anomalies were excluded. Results: In 8 (14%) of 57 cases with recurrent abortions, there were low progesterone levels. In 1 (1.75%) case there was a high androgen level. In 2 (3.5%) cases there was hyperprolactinemia and in another 2 (3.5%) cases there were high insulin levels. In 4 (7%) cases two scores of OGTT were high. In 51 cases where endometrial sampling was performed, only one (1.75%) case had delayed endometrial development. Discussion: We conclude that recurrent abortions have a complex etiology related to endocrinologic and endometrial factors

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