Efficiency of Injection Therapy for Stress Incontinence:a Retrospective Evaluation of 8 Years Results

Aim: To evaluate the long term affectivity of transurethral Calcium Hydrox ylapatite (CaHA; Coaptite®) injection therapy and the predictive importance of Body Mass Index (BMI), menopausal status and previous anti-incontinence surgery in selected female patients with stress urinary incontinence (SUI). Material and Method: Forty-five female patients with SUI, and having high risks for general anesthesia, received transurethal injection therapy, were evaluated retrospectively. First month, 12th month, and 8th year of postinjection period were evaluated in terms of International Consultatiton on Incontinence Questionnaire Short Form (ICIQ-SF), Quality of Life (QoL) score, and pad test. Results: While the pad test of 1st and 12th months’ showed statistically significance, the pad test of last visit was found insignificant, when compared with pre-injection term. Through the evaluations of questionnaire forms similar to the pad test, it was observed that the post- injection scores showed statistically significance. However, unlike to the pad test, for each of both questionnaires, statistically significant differences were detected at the last examination’s scores, as well. When we examined the success of the transurethral injection treatment according to menopausal status, BMI, and previous anti-incontinence surgery, it was observed that QoL and ICIQ-SF score %variation, and 24 hr pad test values did not show any statistically significant differences at long term control, compared with the pre-injection term. Discussion: Transurethral injection is a cheap, easily performed and affective method for selected patients with SUI and BMI, previous anti-incontinence surgery, and menopausal status do not affect transurethral injection results at long term.