Efficacy of low-concentration hypochlorous acid spray in acute sore throat relief

DOI: 10.4328/AEMED.134 Received: 13.04.2018 Accepted: 27.04.2018 Published Online: 28.04.2018 Printed Online: 01.09.2018 J Ann Eu Med 2018;6(3): 37-9 Corresponding Author: Taylan Gun, Ankara Medical Park Hospital, Kentkoop Mah. 1868 Sok. No:15 Batıkent, Ankara, Turkey. T.: +90 3126668000 GSM: +905323435019 F.: +90 3126668666 E-Mail: taylangun@gmail.com Abstract Aim: Sore throat is one of the most predominant symptoms of the human population. The aim of the study was to define the efficacy of low-concentration hypochlorous acid (HOCl) in patients with sore throat. Low-concentration hypochlorous acid (HOCl) is an antiviral and antibacterial agent which is produced endogenously. Material and Method: 50 patients over the age of 18 were included in this study. The patients were randomly chosen to receive oropharyngeal mouthwash with either low-concentration HOCl (n= 24) or placebo saline solution (n= 26) for 4 days. We evaluated the sore throat relief using the 7-point Sore Throat Relief Scale (STRS). Results: The STRS scores were significantly lower in the HOCl group than in the placebo group after 4 days of treatment (p<0.05). Discussion: This study showed that low-concentration HOCl spray provided better improvement in sore throat symptoms when compared to placebo saline spray.