Open AccessLethal midline granuloma
Author(s) -
Caio Paschoalin Trindade,
Rogério Aparecido Dedivitis,
Sílvia Miguéis Picado Petrarolha,
Kauê Moura,
Daniel Herman Partezani
Publication year - 2020
Publication title -
archives of head and neck surgery
Language(s) - English
Resource type - Journals
ISSN - 2595-2544
DOI - 10.4322/ahns.2020.0015
Subject(s) - nose , medicine , lesion , paranasal sinuses , nasal septum , lymphoma , biopsy , radiation therapy , sinus (botany) , pathology , surgery , biology , botany , genus
Lethal midline granuloma is a syndrome with ulcerative vegetative lesion destructing nose, paranasal sinus and palate. Nasal type T-NK cells Lymphoma is often related with this syndrome and without treatment the mortality tax is around 100%. There is association with systemic infection with Epstein Barr Virus. The treatment is the association of radiotherapy and chemotherapy. A 70-year-old male patient presented nose congestion and bleeding with fast growing of an ulcerative lesion in the nose. The computer tomography showed destruction of nose septum and right sinuses. The biopsy diagnosis was nasal type T-NK cells lymphoma.
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