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Drug resistance is a leading concern in control of TB. Resistance against rifampin as one of the most important drugs in the treatment of Mycobacterium tuberculosis is caused by mutations in the 81-base pair region of the rpoB gene encoding the β-subunit of RNA polymerase. This study aimed to characterize the mutations in the rpoB gene associated with rifampin resistance among M. tuberculosis.

ethiopian journal of health sciences

Mutations of &lt;i&gt;rpob&lt;/i&gt; Gene Associated with Rifampin Resistance among&lt;i&gt; Mycobacterium Tuberculosis&lt;/i&gt; Isolated in Tuberculosis Regional Reference Laboratory in Northeast of Iran during 2015-2016