Coinheritance of Β-Thalassemia and Sickle Cell Anaemia in Southwestern Nigeria | Zendy

Osunkalu Vincent | Zendy; Bamisaye E. Oluwaseyi | Zendy; Ayorinde Babatunde James | Zendy; Lawal Saidat | Zendy

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Coinheritance of Β-Thalassemia and Sickle Cell Anaemia in Southwestern Nigeria

Author(s) -

Osunkalu Vincent,

Bamisaye E. Oluwaseyi,

Ayorinde Babatunde James,

Lawal Saidat

Publication year - 2016

Publication title -

ethiopian journal of health sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.479

H-Index - 20

eISSN - 2413-7170

pISSN - 1029-1857

DOI - 10.4314/ejhs.v26i6.3

Subject(s) - thalassemia , asymptomatic , sickle cell anemia , medicine , beta thalassemia , cell , fetal hemoglobin , population , gastroenterology , disease , hemoglobinopathy , pediatrics , immunology , biology , genetics , pregnancy , fetus , environmental health

Genes for haemoglobin S are found in high frequencies in Nigeria. However, there is little information on beta thalassemia in sickle cell anaemia in this population. The clinical presentation of HbS- β thalassemia is enormously variable, ranging from an asymptomatic state to a severe disorder similar to homozygous sickle cell disease.

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