Intraoperative Use of Epsilon Amino Caproic Acid and Tranexamic Acid in Surgeries Performed Under Cardiopulmonary Bypass: a Comparative Study To Assess Their Impact On Reopening Due To Postoperative Bleeding
Author(s) -
Pratiti Choudhuri,
Binay Kumar Biswas
Publication year - 2015
Publication title -
ethiopian journal of health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.479
H-Index - 20
eISSN - 2413-7170
pISSN - 1029-1857
DOI - 10.4314/ejhs.v25i3.11
Subject(s) - tranexamic acid , medicine , anesthesia , cardiopulmonary bypass , aminocaproic acid , antifibrinolytic , perioperative , surgery , caproic acid , blood loss , chemistry , organic chemistry
Open heart surgeries under cardiopulmonary bypass are associated with excessive perioperative bleeding that often requires reoperation. Antifibrinolytics like epsilon aminocaproic acid and tranexamic acid are widely used to control bleeding. There are limited studies primarily showing the impact of these drugs on the incidence of reopening following open heart surgical procedures. The goal of this study was to compare incidence of reopening following open heart surgeries in patients who were administered either epsilon amino caproic acid or tranexamic acid for control of perioperative bleeding.
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