Evidence for expression of endogenous retroviral sequences on primate reproductive tissues and detection of cross-reactive ERVS antigens in the baboon ovary: a review
Author(s) -
Mwenda Jm,
MM Arimi,
Atunga Nyachieo,
DK Langat,
AM Abdi
Publication year - 2006
Publication title -
east african medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.102
H-Index - 40
ISSN - 0012-835X
DOI - 10.4314/eamj.v83i2.9397
Subject(s) - endogenous retrovirus , biology , syncytiotrophoblasts , trophoblast , epididymis , baboon , ovary , placenta , virology , genetics , sperm , genome , gene , pregnancy , fetus , endocrinology
To review recent research findings on the specific expression of endogenous retroviral sequences (ERVS) in reproductive tissues and their possible physiological roles. ERVS have been implicated in several biological events such as induction of resistance to exogenous retrovirus invasion, involvement in placental trophoblast formation, sperm maturation and differentiation; and stimulation of local immunosuppression to protect the foetus from immunological attack.
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