Open AccessA Method To Determine Adhesion Of Suppository Mass On Excised Intestinal Tissue
Author(s) -
JO Onyechi,
Guy-Antonin Martin
Publication year - 2009
Publication title -
animal research international
Language(s) - English
Resource type - Journals
ISSN - 1597-3115
DOI - 10.4314/ari.v6i2.48126
Subject(s) - suppository , adhesion , chemistry , perfusion , chromatography , biomedical engineering , biology , medicine , pharmacology , organic chemistry
A method to determine adhesion of suppository mass to intestinal tissue was developed using excised pig intestine. The method which employs the principle of drainage unto and subsequent detachment from the mucosa, of an adherent suppository mass is simple, inexpensive and accurate. Fully optimised, it can be used to assess differences between suppository formulations, as shown by the preliminary results obtained with commercial Anusol formulations.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom