Effects Of Ceftriaxone On Haematological And Biochemical Parameters Of Turkey

Short-term effects of ceftriaxone on haematological and biochemical parameters of Nigerian local turkey poults were studied. The pre-treatment blood and serum samples were collected and the weight of animals taken before the administration of body weight for a period of 4 days. The animals were weighed daily. The results showed that eosinophilia was significantly increased (P < 0.05) and total bilirubin deceased significantly (P < 0.05). Furthermore, there was significant decrease in chloride ion (P < 0.05) and increase in bicarbonate ion (P < 0.05). Other indices of haematology, liver function test and electrolyte titration were normal (P < 0.05). Ceftriaxone caused eosinophilia in treated samples (2.2 + 0.45 a ) as compared to pre-treated samples (1.6 + 0.89 b ). Total bilirubin in the post-administration samples (13.5 + 1.05 a ) was decreased in comparison with pre-administration samples (14.82 + 0.72 b ). Chloride ion decreased in the treated samples (86.6 + 8.11 a ) when compared with untreated samples (98.4 + 2.88 b ). Bicarbonate ion increased (24.8 + 1.79 a ) in the experimental samples when compared to control (24.4 + 1.34 b ). Conclusively, the short term administration of ceftriaxone may cause eosinophilia, hypobilirubinaemia, hypochloraemia and increased bicarbonate ion which may be positive response to hypochloraemia .