Antibacterial and Anticancer Activity of Bioactive Fraction of Syzygium cumini L. Seeds | Zendy

SUNIL S YADAV | Zendy; GA MESHRAM | Zendy; Dattatraya Shinde | Zendy; RC Patil | Zendy; Sonal M. Manohar | Zendy; Madhav V. Upadhye | Zendy

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Antibacterial and Anticancer Activity of Bioactive Fraction of Syzygium cumini L. Seeds

Author(s) -

SUNIL S YADAV,

GA MESHRAM,

Dattatraya Shinde,

RC Patil,

Sonal M. Manohar,

Madhav V. Upadhye

Publication year - 2011

Publication title -

hayati journal of biosciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.305

H-Index - 17

eISSN - 2086-4094

pISSN - 1978-3019

DOI - 10.4308/hjb.18.3.118

Subject(s) - syzygium , antibacterial activity , chemistry , myrtaceae , fraction (chemistry) , potency , traditional medicine , botany , in vitro , biology , bacteria , biochemistry , organic chemistry , medicine , genetics

Syzygium cumini L. better known as Jamun belonging to the family Myrtaceae is identified to have antidiabetic, anti-inflammatory, anti-pyretic and anti-oxidant activities. Anticancer activity of S. cumini L. fruits has been demonstrated. However, anticancer activity of S. cumini seeds on various types of human cancers has not been explored much. The methanol fraction of ethanol extract from the seeds of S. cumini was found to have significant antibacterial activity. This bioactive fraction was further tested positive for its anticancer activity on various types of human cancer cell lines indicating its potency. Structural characterization of the bioactive fraction was achieved using analysis of high performance liquid chromatography, ultra violet and infra red spectrum

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