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Successful ABO Incompatible Adult Living Donor Liver Transplantation with New Simplified Protocol without Local Infusion Therapy and Splenectomy
Author(s) -
GiWon Song,
SungGyu Lee,
Deok Bog Moon,
Chul Soo Ahn,
Shin Hwang,
Ki Hun Kim,
Tae Yong Ha,
Dong Hwan Jung,
Gil Chun Park,
Jung man Nam-Gung,
Sam Yeol Yoon,
Sung-Won Jung
Publication year - 2011
Publication title -
korean journal of transplantation
Language(s) - English
Resource type - Journals
eISSN - 2671-8804
pISSN - 2671-8790
DOI - 10.4285/jkstn.2011.25.2.95
Subject(s) - living donor liver transplantation , splenectomy , abo blood group system , transplantation , liver transplantation , medicine , spleen
Results: There was 1 case of in-hospital mortality (2.3%) among the 43 cases. Overall 3-month and 1-year patient and graft survival rate was 97.7% and 92.1% during a mean period of 11.4 ± 0.4 (0.9∼28.9) months. There was no significant difference in the 3-month and 1-year patient and graft survival rates (95.0 vs. 100% and 90.0 vs. 92.9%, P=0.60) between groups. LIT-related complications occurred in 4 patients (20.0%). One case of antibody-mediated rejection occurred in group II. Both groups showed no difference in graft function at postoperative 3rd month. Conclusions: ABOi ALDLT without splenectomy and LIT resulted in promising outcomes. Therefore, LIT can be safely eliminated from the protocol.

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