Six-Year Analysis of the Seropositivity of HBV, HCV, HIV, and Syphilis in Volunteer Blood Donors Attending Our Blood Center

OZET Kan Merkezimize Basvuran Gonullu Kan Bagiscilarinda Alti Yillik HBV, HCV, HIV ve Sifiliz Seropozitifliginin Degerlendirilmesi Amac: Alti yil icinde kan hizmet birimimizde kan bagisi yapan gonullu bagiscilarda saptanan mikrobiyolojik tarama testlerindeki pozitiflik oraninin ulkemiz ortalamalari ile karsilastirilmasidir. Gerec ve Yontemler: Bu kesitsel calismaya 2007-2013 yillari arasinda kan merkezimize basvuran 45.632 gonullu kan donoru alinmistir. Gonullu donorlerden alinan her ornekten HBsAg, Anti HCV ve Anti HIV 1-2 testleri kemiluminesan mikropartikul enzim immunoassay (CMIA) yontemi ile calisilmistir. Sifiliz icin taramada ilk dort yilda nontreponemal karbon slide testi, son iki yilda ise CMIA temeline dayali bir treponemal test (Architect Syphilis TP; Abbott) kullanilmistir. Bulgular: Tum bagiscilarin 743’unde (%1,62) tarama testlerinden biri pozitif bulunmustur. HBsAg, Anti-HCV, Sifiliz ve Anti-HIV 1, 2 seropozitiflikleri sirasiyla %1,01, %0,51, %0,09, %0,004 olarak saptanmistir. Sonuc: Saptadigimiz oranlar ulkemiz genelinde Viral Hepatit Savasim Dernegi’nin calismalarina gore bulunan HBsAg seropozitifligine gore dusuk, Anti-HCV seropozifligine gore ise benzer bulunurken, sifiliz ve anti-HIV seropozitiflik oranlari ulkemizde yapilan degisik calismalarla uyumlu olarak bulunmustur. Anahtar Kelimeler: kan bagiscilari, HBsAg, anti-HCV, anti-HIV, RPR Cikar catismasi: Yazarlar bu makale ile ilgili olarak herhangi bir cikar catismasi bildirmemislerdir. Objective: To compare the seropositivity rates detected by microbiologic screening tests performed in a six-year period in volunteer blood donors in our blood center with the rates in the general population in Turkey. Materials and Methods: This cross-sectional study included 45.632 volunteer blood donors who attended our blood center between 2007 and 2013. Each sample from volunteer donors was tested for HBsAg, anti-HCV, and anti-HIV 1 and 2 by the chemiluminescent microparticle enzyme immunoassay (CMIA) method. The screening for syphilis was done by a nontreponemal test for the first four years and, then, by CMIA-based treponemal test (Architect Syphilis TP; Abbott) for the last two years. Results: Out of all donors, 743 (1.62%) was found to be positive for at least one screening test. Seropositivity rates for HBsAg, Anti-HCV, anti-HIV 1, 2, and syphilis were 1.01%, 0.51%, 0.09%, and 0.004%, respectively. Conclusion: The rate of HbsAg positivity was low compared to that in the general population reported by the National Viral Hepatitis Prevention Association. The anti-HCV, syphilis, and anti-HIV positivity rates found in this study were compatible with the results of the studies performed on the general population.