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Prostate cancer is the most common malignancy among elderly men and the second leading cause of cancer deaths in men after lung cancer (1,2). Transrectal ultrasonography (TRUS)guided prostate needle biopsy is used as a standard method in the diagnosis of prostate cancer. Although this technique is minimally invasive, it can cause the patient severe pain both during and after the procedure (3). Pain usually occurs when the ultrasound probe is introduced into the rectum, during probe manipulations, and when the biopsy needle contacts the prostate (4).

Comparison of Lidocaine and Prilocaine Efficiencies in Periprostatic Nerve Block for Transrectal Prostate Biopsy: A Randomized Prospective Study