Positron Emission Tomography/Computed Tomography in Bladder Carcinoma

Bu derlemenin amaci; literaturdeki sistemik derleme ve metaanalizler kilavuzlugunda mesane kanserinde pozitron emisyon tomografisi-bilgisayarli tomografinin (PET-BT) rolunu tartismaktir. Florodeoksiglukozun (FDG) idrar ile atilmasi nedeniyle uriner sistem kanserlerinin tanisinda FDG PET-BT sinirli role sahiptir. Fakat diuretik ve oral hidrasyonla F-18 FDG’nin mesaneden uzaklastirilmasinin, PETBT ile mesane kanseri goruntuleme ve yeniden evrelemede rolu vardir. Lokal lenf nodu metastazi mesane kanserinde onemli prognostik degere sahiptir. Preoperatif metastatik hastalik tanimlayabilmek tedaviyi belirleyen en onemli noktadir. Preoperatif evrelemeye bagli tedavi, yasam suresini degistirebilir. Anah tar Ke li me ler: Pozitron emisyon tomografisi-bilgisayarli tomografi (PET-BT), mesane kanseri The purpose of the current review was to conduct a systemic review and meta-analysis of the published literature to discuss the role of positron emission tomography (PET) or positron emission tomographycomputed tomography (PET/CT) in urinary bladder cancer. PET/CT has a limited role in the detection of urinary system cancers because fluorodeoxyglucose (FDG) is excreted with urine. However removal of F-18 FDG from the bladder with diuretic and oral hydration has a role in the detection and restaging of bladder cancer with PET/CT. Locoregional lymph node metastasis is an important prognostic factor in patients with bladder cancer. The ability to identify metastatic disease preoperatively is of utmost importance in determining treatment. Multimodal treatment, depending on preoperative stage, may improve survival.