Microwave-assisted Preparation of Cross-linked Gelatin-Paracetamol Matrices: Optimization Using the D-optimal Design | Zendy

Tan Kian KUANG | Zendy; Y. B. Kang | Zendy; Ignacio Segarra | Zendy; Ummarah Kanwal | Zendy; Muhammad Ahsan | Zendy; Nadeem Irfan Bukhari | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Microwave-assisted Preparation of Cross-linked Gelatin-Paracetamol Matrices: Optimization Using the D-optimal Design

Author(s) -

Tan Kian KUANG,

Y. B. Kang,

Ignacio Segarra,

Ummarah Kanwal,

Muhammad Ahsan,

Nadeem Irfan Bukhari

Publication year - 2020

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.galenos.2020.48902

Subject(s) - gelatin , microwave , chromatography , chemistry , materials science , computer science , organic chemistry , telecommunications

This study was conducted to assess the effect of microwave heating on the preparation of paracetamol cross-linked gelatin matrices by using the design of experiment (DoE) approach and explore the influence of the duration of microwave irradiation, the concentrations of crosslinker, and the amount of sodium bicarbonate (salt) on paracetamol release. These parameters were also compared with those of the matrices prepared via conventional heating.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research