QbD-based Formulation Optimization and Characterization of Polymeric Nanoparticles of Cinacalcet Hydrochloride with Improved Biopharmaceutical Attributes | Zendy

Debashish Ghose | Zendy; Chinam Niranjan Patra | Zendy; Bera Varaha Venkata Ravi Kumar | Zendy; Suryakanta Swain | Zendy; Bikash Ranjan Jena | Zendy; Punam CHOUDHURY | Zendy; Dipthi Shree | Zendy

Open Access

QbD-based Formulation Optimization and Characterization of Polymeric Nanoparticles of Cinacalcet Hydrochloride with Improved Biopharmaceutical Attributes

Author(s) -

Debashish Ghose,

Chinam Niranjan Patra,

Bera Varaha Venkata Ravi Kumar,

Suryakanta Swain,

Bikash Ranjan Jena,

Punam CHOUDHURY,

Dipthi Shree

Publication year - 2020

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.galenos.2020.08522

Subject(s) - biopharmaceutical , characterization (materials science) , nanoparticle , materials science , nanotechnology , microbiology and biotechnology , biology

The aim of the present work was to prepare QbD enabled optimization, and to improve the oral bioavailability of freeze-dried polymeric nanoparticles of cinacalcet hydrochloride manufactured by nanoprecipitation and ultrasonication methods using polymers PLGA, and poloxamer-188.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research