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Hydrogels are macromolecular networks able to absorb and release water/biological fluids in a reverse-phase manner, in response to specific environmental stimuli. Such stimuli-sensitive behavior makes hydrogels interesting for the design of smart devices applicable to a variety of technological fields. They are able to absorb and retain 10-20% and up to 1000 times the water or biological fluids than their dry weight can. The aim of this study was to extend the work on drug delivery in the stomach at pH 2-2.2.

Synthesis and Swelling Behavior of Sodium Alginate/Poly(vinyl alcohol) Hydrogels