Superior Solubility and Dissolution of Zaltoprofen via Pharmaceutical Cocrystals | Zendy

Prabhakar Panzade | Zendy; Giridhar Shendarkar | Zendy

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Superior Solubility and Dissolution of Zaltoprofen via Pharmaceutical Cocrystals

Author(s) -

Prabhakar Panzade,

Giridhar Shendarkar

Publication year - 2019

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.galenos.2018.15013

Subject(s) - solubility , dissolution , melting point , differential scanning calorimetry , crystallization , crystallinity , powder diffraction , cocrystal , materials science , chemistry , nuclear chemistry , chemical engineering , organic chemistry , crystallography , molecule , thermodynamics , hydrogen bond , physics , engineering

Pharmaceutical cocrystals are a promising tool to enhance the solubility and dissolution of poorly soluble drugs. Zaltoprofen (ZFN) is nonsteroidal anti-inflammatory drug with a prevalent solubility problem. The present study was undertaken to enhance the solubility and dissolution of ZFN through pharmaceutical cocrystals by screening various coformers.

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