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Quetiapine Fumarate Extended-release Tablet Formulation Design Using Artificial Neural Networks
Author(s) -
Esher ÖZÇELİK,
Burcu Mesut,
Buket Aksu,
Yıldız Özsoy
Publication year - 2017
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.97720
Subject(s) - artificial neural network , scope (computer science) , quality by design , computer science , quetiapine fumarate , immediate release , biochemical engineering , artificial intelligence , engineering , chemistry , chemical engineering , chromatography , particle size , programming language , schizophrenia (object oriented programming) , atypical antipsychotic , antipsychotic
This design study was implemented within the scope of the quality by design approach, which included the "International Conference on Harmonization" guidelines. We evaluated the quality of a modified-release tablet formulation of quetiapine fumarate, which was designed using artificial neural networks (ANN), and determined a new formulation that was similar to the reference product.

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