Subcutaneous Toxicity of Agmatine in Rats
Author(s) -
Tayfun Uzbay,
Fatma Duygu Kaya Yertutanol,
Ahmet Midi,
Burcu Çevreli
Publication year - 2017
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.85057
Subject(s) - agmatine , toxicity , subcutaneous injection , saline , pharmacology , medicine , necrosis , anesthesia , intraperitoneal injection , pathology , chemistry , biochemistry , enzyme , putrescine
The aim of this study was to investigate the effects of repetitive agmatine administration on sensorimotor gating in rats first but, as unexpected, ulcerative necrotic cutaneous lesions appeared, thus, the study was directed primarily to clarify these results.
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