Assessment of Vitronectin, Soluble Epithelial-Cadherin and TGF-β1 as a Serum Biomarker with Predictive Value for Endometrial and Ovarian Cancers
Author(s) -
Taylan Turan,
Meral Torun,
Funda Atalay,
Aymelek Gönenç
Publication year - 2017
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.81994
Subject(s) - biomarker , vitronectin , cadherin , epithelial ovarian cancer , predictive value , medicine , endometrial cancer , oncology , cancer research , ovarian cancer , cancer , biology , receptor , cell , integrin , biochemistry , genetics
Extracellular matrix components, including vitronectin (VN), soluble epithelial-cadherin (sE-cadherin) and transforming growth factor-beta 1 (TGF-β1), play a key role in the invasion and metastasis of cancer. The objective of the study was to determine the clinical significance of serum levels of these molecules in patients with endometrial and ovarian cancers.
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