Development And Characterization Of Insulin-Loaded Liposome-Chitosan Nanoparticle (LCS-NP) Complex And Investigation Of Transport Properties Through Pancreatic Beta TC Cell Line | Zendy

Merve Çelik Tekeli | Zendy; Çiğdem Yücel | Zendy; Sedat Ünal | Zendy; Yeşim Aktaş | Zendy

Open Access

Development And Characterization Of Insulin-Loaded Liposome-Chitosan Nanoparticle (LCS-NP) Complex And Investigation Of Transport Properties Through Pancreatic Beta TC Cell Line

Author(s) -

Merve Çelik Tekeli,

Çiğdem Yücel,

Sedat Ünal,

Yeşim Aktaş

Publication year - 2018

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.70783

Subject(s) - insulin , zeta potential , liposome , particle size , in vitro , materials science , chemistry , nuclear chemistry , nanoparticle , chromatography , biophysics , biochemistry , medicine , nanotechnology , biology

In recent years, studies on oral use have increased rapidly due to the restrictive aspects of parenteral administration of indispensable peptide-structured insulin in the rapidly growing worldwide treatment of diabetes. The aim of the study was to examine the development of a novel insulin-loaded LCS-NP complex, and its characterization and efficacy on pancreatic cells responsible for insulin release.

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