Antimicrobial Activities of New Indole Derivatives Containing 1,2,4-Triazole, 1,3,4-Thiadiazole and Carbothioamide | Zendy

Hanif Shirinzadeh | Zendy; Síbel Süzen | Zendy; Nurten Altanlar | Zendy; Andrew D. Westwell | Zendy

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Antimicrobial Activities of New Indole Derivatives Containing 1,2,4-Triazole, 1,3,4-Thiadiazole and Carbothioamide

Author(s) -

Hanif Shirinzadeh,

Síbel Süzen,

Nurten Altanlar,

Andrew D. Westwell

Publication year - 2018

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.55707

Subject(s) - antimicrobial , fluconazole , candida albicans , triazole , indole test , chemistry , ciprofloxacin , candida krusei , thiazole , serial dilution , bacillus subtilis , microbiology and biotechnology , candida tropicalis , combinatorial chemistry , antifungal , biology , stereochemistry , medicine , organic chemistry , bacteria , antibiotics , alternative medicine , genetics , pathology

In new antimicrobial drug development studies, indole and its derivatives create an important class of compounds. In addition, azoles and their derivatives were recognized to be associated with a variety of biologic activities such as antibacterial and antifungal. In this study antimicrobial activities of some indole derivatives mainly substituted with 1,2,4-triazole, 1,3,4-thiadiazole and hydrazinecarbothioamide were investigated to evaluate their efficacy.

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