Open AccessActivation of Two Different Drugs Used in Alzheimer’s Disease Treatment on Human Carbonic Anhydrase Isozymes I and II Activity: an <i>In Vitro</i> Study
Author(s) -
Esra Dilek
Publication year - 2017
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.43434
Subject(s) - donepezil , carbonic anhydrase , in vitro , isozyme , pharmacology , disease , medicine , chemistry , enzyme , biochemistry , dementia
Human carbonic anhydrase I and II (hCAI, II) isoenzymes were purified from human erythrocyte. Kinetic interactions between the enzymes and memantine and donepezil, two different drugs used in Alzheimer's disease (AD) treatment, were investigated.
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