Preparation and in vitro evaluation of ibuprofen spherical agglomerates | Zendy

Subhash Chandra Bose Penjuri | Zendy; Damineni Saritha | Zendy; R. Nagaraju | Zendy; Raja Lakshmi Muni | Zendy; Srikanth Reddy Poreddy | Zendy

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Preparation and in vitro evaluation of ibuprofen spherical agglomerates

Author(s) -

Subhash Chandra Bose Penjuri,

Damineni Saritha,

R. Nagaraju,

Raja Lakshmi Muni,

Srikanth Reddy Poreddy

Publication year - 2018

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.09609

Subject(s) - ibuprofen , agglomerate , dissolution , solubility , solvent , dichloromethane , chemistry , materials science , chemical engineering , nuclear chemistry , organic chemistry , pharmacology , composite material , medicine , engineering

Ibuprofen, an anti-inflammatory drug, is characterized by poor water solubility, which limits its pharmacologic effects. The present work aimed to the study the effect of agglomeration on the micromeritic properties and dissolution of ibuprofen.

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