Assessment of Cytotoxicity Profiles of Different Phytochemicals: Comparison of Neutral Red and MTT Assays in Different Cells in Different Time Periods | Zendy

Merve Bacanlı | Zendy; Hatice Gül Anlar | Zendy; Arif Ahmet Başaran | Zendy; Nurşen Başaran | Zendy

Open Access

Assessment of Cytotoxicity Profiles of Different Phytochemicals: Comparison of Neutral Red and MTT Assays in Different Cells in Different Time Periods

Author(s) -

Merve Bacanlı,

Hatice Gül Anlar,

Arif Ahmet Başaran,

Nurşen Başaran

Publication year - 2017

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.07078

Subject(s) - galangin , neutral red , cytotoxicity , mtt assay , hela , viability assay , incubation , chinese hamster , curcumin , cell culture , chemistry , traditional medicine , incubation period , pharmacology , biochemistry , quercetin , biology , in vitro , antioxidant , medicine , kaempferol , genetics

Phenolic compounds exhibit several health protective properties. Galangin, curcumin, pycnogenol, puerarin and ursolic acid are commonly used plant phenolics in folk medicine. The aim of our study was to evaluate the difference between neutral red uptake (NRU) and MTT assays using different plant phenolics (galangin, curcumin, pycnogenol, puerarin and ursolic acid) in healthy and cancer cells in different time periods.

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