Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study | Zendy

Sefa Arlıer | Zendy

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Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study

Author(s) -

Sefa Arlıer

Publication year - 2017

Publication title -

journal of turkish society of obstetric and gynecology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.41

H-Index - 9

eISSN - 1307-7007

pISSN - 1307-699X

DOI - 10.4274/tjod.78545

Subject(s) - leptin , medicine , endocrinology , leptin receptor , endothelial stem cell , preeclampsia , endothelial dysfunction , umbilical vein , receptor , proinflammatory cytokine , biology , inflammation , pregnancy , in vitro , obesity , biochemistry , genetics

Increased leptin hormone and leptin receptor may enhance the generation of proinflammatory cytokines by endothelial cells and lead to endothelial dysfunction. This study assessed the umbilical cord endothelial leptin receptor levels in preeclampsia and investigated the effect of leptin on endothelial interleukin-8 (IL-8) production.

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