Amniyon Membran Transplantasyonu Endikasyonlarımız ve Sonuçlarımız

Objectives: To investigate the indications and outcomes of amniotic membrane transplantation (AMT).\udMaterials and Methods: A total of 87 eyes who underwent amnion membrane transplantation in our clinic between February 2010\udand April 2013 were included in this study. Mean follow-up period was 7.49±7.84 months (range 1-29 months). Amnion membrane\uddefrosted at room temperature and washed three times with saline covered all over the cornea independent of the position and size\udof the lesion and was sutured to the peripheral cornea circumferentially by 10/0 monofilament suture. At the end of the operation,\udtherapeutic contact lens was placed. All cases were evaluated with respect to duration of surface epithelial healing, visual acuity, presence\udof recurrence, and infection.\udResults: Forty-six of the 87 patients (52.8%) were men and 41 (47.1%) were women. The mean age was 57.02±19.74 years (range\ud31-89 years) in men and 66.69±16.56 years (range 8-88 years) in women. The indications were: ulcers in 27 eyes, keratitis in 24 eyes,\udtopical anesthetic abuse in 10 eyes, bullous keratopathy in 7 eyes, conjunctival mass in 7 eyes, symblepharon in 3 eyes, chemical burns\udin 3 eyes, pterygium in 2 eyes, endophthalmitis in 2 eyes, dellen in 1 eye, and conjunctival laceration in 1 eye. After AMT, 12 patients\udrequired second AMT, and 2 cases required third AMT. 2 eyes were eviscerated, 1 eye was exenterated. At the final follow-up visit,\udexcept for patients who underwent evisceration and exenteration, improved visual acuity was observed in 45 of the 84 eyes (53.5%).\udThe average of healing time was between 4 and 6 weeks. No infectious, inflammatory, immunologic, or toxic/allergic reactions related\udto AMT was observed.\udConclusion: Amniotic membrane transplantation is a safe and effective technique in ocular surface diseases. (Turk J Ophthalmol\ud2014; 44: 123-