Comet Lesions in Patients with Pseudoxanthoma Elasticum | Zendy

Sinan Tatlıpınar | Zendy; Berna Şahan | Zendy; Muhsin Altunsoy | Zendy

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Comet Lesions in Patients with Pseudoxanthoma Elasticum

Author(s) -

Sinan Tatlıpınar,

Berna Şahan,

Muhsin Altunsoy

Publication year - 2015

Publication title -

turkish journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.654

H-Index - 10

eISSN - 2147-2661

pISSN - 1300-0659

DOI - 10.4274/tjo.84756

Subject(s) - pseudoxanthoma elasticum , angioid streaks , pathognomonic , medicine , fundus (uterus) , choroidal neovascularization , ophthalmology , metamorphopsia , dermatology , pathology , visual acuity , disease

Pseudoxanthoma elasticum (PXE) is a genetic multisystemic disorder affecting the skin, eyes and cardiovascular system. Basic fundoscopic findings in PXE result from Bruch's membrane involvement. The most important fundoscopic findings are angioid streaks. Other significant ocular findings are peau d'orange appearance, optic disc drusen, pattern dystrophy-like macular appearance, comet lesions, and choroidal neovascularization. Comet lesions are a pathognomonic ocular finding for PXE. The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. Herein, we present two PXE cases with comet lesions.

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