Viskoelastik Maddeye Bağlı Gelişen Toksik Anterior Segment Sendromu

Objectives: To evaluate the etiologic factors of toxic anterior segment syndrome (TASS) outbreak after uneventful cataract surgery, to\uddiscuss the treatment plan, and to assess the response to medical therapy.\udMaterials and Methods: Clinical features in twenty-two eyes of 22 patients who had TASS outbreak after uneventful cataract surgery\udwere evaluated. Visual acuity (VA), intraocular pressure (IOP) measurements, biomicroscopic and B-mode ultrasound evaluations were\udperformed. To establish the differential diagnosis from infectious endophthalmitis, cultures were taken from different subjects such\udas surgical equipment, solutions, medical devices. All patients were treated as having endophthalmitis until the culture results were\udobtained.\udResults: Based on the negative culture results, absence of any symptoms of TASS in other patients who underwent different intraocular\udsurgeries rather than cataract surgery in the same day and same surgical condition in which VES was not used, and the fact that\udpostoperative inflammation occurred only in eyes in which the new VES made of rooster comb was used, we assume that the recently\udused VES is most likely responsible for the TASS outbreak. As soon as another VES was replaced with the suspected one, no other cases\udwith TASS occurred.\udConclusion: Even though the chemical compositions of VES are in physiological limits for viability to the anterior segment tissue, the\udsuboptimal or inappropriate storage conditions may cause loss of the original chemical integrity which can be the reason of TASS. Close\udmonitoring of each patient, early diagnosis, and correct treatment can prevent its complications. (Turk J Ophthalmol 2014; 44: 341-6