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Prostaglandin analogues, latanoprost and travoprost, and one of the prostamides, bimatoprost, are widely used in glaucoma practice with\udtheir efficacious intraocular pressure-lowering effect. Treatment-related trichomegaly, increase in periocular pigmentation and adnexal hair\udgrowth are well-known periocular changes. But recently, a new and infrequent side effect called prostaglandin-associated periorbitopathy\udcharacterized by deepening of the upper lid sulcus, ptosis, enophthalmus, regression in dermatochalasis and lower lid lateral orbital fat pad\udprolapsus has been determined. In this case report, we wanted to present this rare side effect in three glaucoma patients who received\udbimatoprost and travoprost and to remind related fundamental physiopathology. (Turk J Ophthalmol 2013; 43: 57-60

Prostaglandin İlişkili Periorbitopati: Olgu Sunumu ve Temel Fizyopatolojik Hatırlatma