Katarakt Cerrahisi Öncesi Kullanılan Topikal %2,5'luk Fenilefrin HCI Damlanın Sistemik Kan Basıncına Etkisi

Purpose: To evaluate the effect of topical phenylephrine HCl 2.5% (Mydfrin), used as a fast and effective mydriatic before\udcataract surgery, on systemic blood pressure.\udMaterial and Method: Topical phenylephrine HCl 2.5% was administered 3 times with 5-minute intervals before cataract\udsurgery to 44 eyes of 44 patients. The systemic blood pressure was measured preoperatively and at 15 and 30 minutes.\udResults: The mean systolic blood pressure before the topical administration of phenylephrine HCl 2.5% was\ud119.7mmHg, while 15 and 30 minutes later, it was 125.3 mmHg and 121.2 mmHg, respectively. The mean diastolic\udblood pressure before the topical administration of phenylephrine HCl 2.5% was 75.9 mmHg; 15 and 30 minutes later,\udit was 76.9 mmHg and 75.3 mmHg, respectively. The increase in systolic blood pressure at 15 and 30 minutes was statistically\udsignificant (p=0.003 and p=0.042). The change in diastolic blood pressure was not statistically significant.\udDiscussion: Phenylephrine HCl 2.5%, which is used preoperatively as a fast and effective mydriatic for cataract surgery, can\udincrease the systolic blood pressure. This effect is most significant at 15 minutes and lasts at least 30 minutes. This agent should\udbe used with care in hypertensive patients. (Turk J Ophthalmol 2011; 41: 164-6