Extranodal Natural Killer/T-Cell Lymphoma: A Rare Nasal-Type Case
Author(s) -
Esra Sarıbacak Can,
Harika Okutan,
Murat Albayrak,
Ünsal Han
Publication year - 2016
Publication title -
turkish journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.351
H-Index - 16
ISSN - 1300-7777
DOI - 10.4274/tjh.2015.0169
Subject(s) - medicine , lymphoma , natural killer t cell , dermatology , pathology , immunology , t cell , immune system
Nasal type extranodal natural killer (NK) NK-cell/T-cell\udlymphoma (NKTCL) is a rare extranodal lymphoma of NK-cell\udor T-cell origin that most commonly affects immunocompetent\udmiddle-aged men of Asian or Native American descent [1]. The\udpathogenesis is not understood completely, but it is related\udin part to infection of the tumor cells with Epstein-Barr virus\ud(EBV) [2]. Around 6-7% of all non-Hodgkin’s lymphoma (NHL)\udin Southeast Asia accounts for NKTCL. However, the incidence of\udNHL is lower in the United States at 1.5% [3,4].\udDisease within the nasal cavity has a better prognosis. Radiation\udtherapy alone can be curative. Over 60% of patients with stage\ud1 disease remain in long-term remission following treatment\udwith radiation therapy with or without chemotherapy [5].\udNasal disease may be cured with radiotherapy at a rate of 85%.\udHowever, the relapse rate is high at 25%. Therefore, it is highly\udcrucial for this aggressive disease to be diagnosed and treated\udat an early stag
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