Megadose Methylprednisolone (MDMP) Treatment in a Patient with Autoimmune Hemolytic Anemia (AIHA) Resistant to Conventional Corticosteroid Administration: A Case Report | Zendy

Şînasi Özsoylu | Zendy; Henriette W Berenschot | Zendy

Open Access

Megadose Methylprednisolone (MDMP) Treatment in a Patient with Autoimmune Hemolytic Anemia (AIHA) Resistant to Conventional Corticosteroid Administration: A Case Report

Author(s) -

Şînasi Özsoylu,

Henriette W Berenschot

Publication year - 2013

Publication title -

turkish journal of hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.351

H-Index - 16

ISSN - 1308-5263

DOI - 10.4274/tjh.2012.0070

Subject(s) - medicine , methylprednisolone , autoimmune hemolytic anemia , corticosteroid , anemia , gastroenterology , anesthesia , gynecology

A female in the Netherlands with severe autoimmune hemolytic anemia (AIHA) was treated with conventional corticosteroid (2 mg/kg/d in divided doses) and blood transfusions for 18 months without improvement. The presented patient responded to megadose methylprednisolone (MDMP) 30 mg/kg/d for 3 d, followed by 20 mg/kg for 4 d, and subsequently 10, 5, 2, and 1 mg/kg/d each for 1 week.

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