Comparison of Electrochemiluminescence and Enzyme Immunoassay Methods for the Measurement of Salivary Cortisol | Zendy

Gülşah Elbüken | Zendy; Kader Köse | Zendy; Züleyha Karaca | Zendy; Fatih Tanrıverdi | Zendy; Kürşad Ünlühızarcı | Zendy; Gökmen Zararsız | Zendy; Fahrettin Keleştimur | Zendy

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Comparison of Electrochemiluminescence and Enzyme Immunoassay Methods for the Measurement of Salivary Cortisol

Author(s) -

Gülşah Elbüken,

Kader Köse,

Züleyha Karaca,

Fatih Tanrıverdi,

Kürşad Ünlühızarcı,

Gökmen Zararsız,

Fahrettin Keleştimur

Publication year - 2014

Publication title -

turkish journal of endocrinology and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.111

H-Index - 5

ISSN - 1301-2193

DOI - 10.4274/tjem.2556

Subject(s) - immunoassay , electrochemiluminescence , medicine , microbiology and biotechnology , gynecology , chemistry , chromatography , immunology , biology , antibody , detection limit

Purpose: The aim of the study was to compare electrochemiluminescence (ECL) and enzyme immunoassay (EI) methods for the measurement of salivary cortisol (SC).\udMaterial and Method: SC levels in 20 healthy subjects were measured by two different methods (EI and ECL).\udResults: The results obtained from EI and ECL methods were found to be significantly correlated.\udDiscussion: Measuring SC by ECL method is faster and easier than EI in routine practice. Therefore, SC measured by ECL rather than EI may be used as a marker of hypothalamic-pituitary-adrenal (HPA) axis function

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