Cranium Metastasis: An Unusual Presentation of Differentiated Thyroid Carcinoma

Turkish Journal of Endocrinology and Metabolism, published by Galenos Publishing. Address for Correspondence/Yazışma Adresi: Ayşe Kubat Üzüm MD, İstanbul University Medical Faculty, Department of Internal Medicine, Division of Endocrinology and Metabolism, İstanbul, Turkey Phone: +90 212 414 20 00/32735 E-mail: akubatuzum@yahoo.com Recevied/Geliş Tarihi: 10.02.2013 Accepted/Kabul Tarihi: 24.03.2013 Abs tract Distant metastasis may be the initial sign of differentiated thyroid carcinoma in rare cases. In this instance, the treatment approach is usually individualized. Unlike most other cancers, local treatment of the primary tumor (total thyroidectomy) is preferred as ablative surgery; so that radioactive iodine therapy should be more effective. Repeated doses of I-131 and radiotherapy for metastatic lesions may be needed. We report a female who presented with bone metastasis with fatal progression. Turk Jem 2013; 17: 71-4