The Diagnostic Value of the Correlation between Serum Anti-p53 Antibody and Positron Emission Tomography Parameters in Lung Cancer
Author(s) -
Zekiye Hasbek,
Ömer Tamer Doğan,
İsmail Sarı,
Birsen Yücel,
Mehmet Şeker,
Bülent Turgut,
Serdar Berk,
Yavuz Siliğ
Publication year - 2016
Publication title -
molecular imaging and radionuclide therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 7
eISSN - 2147-1959
pISSN - 2146-1414
DOI - 10.4274/mirt.97269
Subject(s) - medicine , lung cancer , standardized uptake value , positron emission tomography , nuclear medicine , cancer , fluorodeoxyglucose , lung , solitary pulmonary nodule , radiology
Mutations in the p53 gene are the most commonly observed genetic abnormalities in malignancies. The purpose of this study was to assess the diagnostic value of serum anti-p53 antibody (Ab) along with the correlation between serum anti-p53 Ab level and quantitative positron emission tomography (PET) parameters such as maximum standardized uptake value (SUVmax), SUVave, metabolic tumor volume, total lesion glycolysis (TLG) and tumor size.
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