Paratiroid Adenomunda Oktreotid Tutulumu
Author(s) -
Seyhan Karaçavuş,
Mustafa Kula,
Züleyha Karaca,
Unluhizarci Kursad,
Ahmet Tutuş,
Fahrı Bayram,
Ganime Çoban
Publication year - 2012
Publication title -
molecular imaging and radionuclide therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 7
eISSN - 2147-1959
pISSN - 2146-1414
DOI - 10.4274/mirt.4
Subject(s) - octreotide , medicine , scintigraphy , bone scintigraphy , osteomalacia , somatostatin receptor , parathyroid adenoma , thyroid , adenoma , nuclear medicine , somatostatin , radiology , pathology , endocrinology , vitamin d and neurology
The patient with a history of bone pain and muscle weakness, was thought to have oncogenic osteomalacia as a result of biochemical investigations and directed to Nuclear Medicine Department for a whole-body bone scintigraphy and 111In-octreotide scintigraphy. There was no focal pathologic tracer uptake, but generalized marked increase in skeletal uptake on bone scintigraphy. Octreotide scintigraphy showed accumulation of octreotide in the region of the left lobe of the thyroid gland in the neck. Thereafter, parathyroid scintigraphy was performed with technetium-99m labeled metroxy-isobutyl-isonitryl (99mTc-MIB) and MIBI scan demonstrated radiotracer uptake at the same location with octreotide scintigraphy. The patient underwent left inferior parathyroidectomy and histopathology confirmed a parathyroid adenoma. Somatostatin receptor positive parathyroid adenoma may show octreotide uptake. Octreotide scintigraphy may be promising and indicate a possibility of using somatostatin analogues for the medical treatment of somatostatin receptor positive Conflict of interest:None declared.
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