Disseminated Multi-system Sarcoidosis Mimicking Metastases on 18F-FDG PET/CT | Zendy

William Makis | Zendy; Mark Palayew | Zendy; Christopher Rush | Zendy; Stephan Probst | Zendy

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Disseminated Multi-system Sarcoidosis Mimicking Metastases on 18F-FDG PET/CT

Author(s) -

William Makis,

Mark Palayew,

Christopher Rush,

Stephan Probst

Publication year - 2018

Publication title -

molecular imaging and radionuclide therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.292

H-Index - 7

eISSN - 2147-1959

pISSN - 2146-1414

DOI - 10.4274/mirt.29200

Subject(s) - medicine , sarcoidosis , malignancy , radiology , positron emission tomography , fluorodeoxyglucose , bone marrow , lung , biopsy , pet ct , spleen , nuclear medicine , lymphoma , pathology

A 60-year-old female with no significant medical history presented with hematuria. A computed tomography (CT) scan revealed extensive lymphadenopathy with hypodensities in the liver and spleen, and she was referred for an 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography/CT (PET/CT) study to assess for malignancy of unknown primary. PET/CT revealed extensive 18 F-FDG avid lymphadenopathy as well as innumerable intensely 18 F-FDG avid lung, liver and splenic nodules, highly concerning for malignancy. A PET-guided bone marrow biopsy of the posterior superior iliac spine revealed several non-necrotizing, well-formed granulomas, consistent with sarcoidosis. The patient was managed conservatively and remained clinically well over the subsequent 9 years of follow-up.

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