Open AccessHypermetabolic Calcified Lymph Nodes on 18Fludeoxyglucose-Positron Emission Tomography/Computed Tomography in a Case of Treated Ovarian Cancer Recurrence: Residual Disease or Benign Formation?
Author(s) -
Alexandra V. Nikaki,
A. Alexopoulos,
Fani Vlachou,
Vasiliki P. Filippi,
Ioannis Andreou,
Vasiliki Rapti,
K. Gogos,
K. Dalianis,
Roxani D. Efthymiadou,
Vassilios Prassopoulos
Publication year - 2016
Publication title -
molecular imaging and radionuclide therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 7
eISSN - 2147-1959
pISSN - 2146-1414
DOI - 10.4274/mirt.22932
Subject(s) - medicine , positron emission tomography , nuclear medicine , ovarian cancer , radiology , lymph , cancer , pathology
The contribution of positron emission tomography/computed tomography (PET/CT) with 18F-fludeoxyglucose (FDG) in evaluating ovarian cancer recurrence even after a prolonged disease-free interval, and in therapy response is well-described. Calcifications observed in CT, although usually attributed to benign conditions, may actually represent active disease. Such an example of calcified formations is psammoma bodies. We present a case of 56-y. o. patient with ovarian cancer relapse at the supraclavicular area 18 years after complete response and disease-free interval. The patient received chemotherapy and underwent 18F-FDG-PET/CT for the evaluation of treatment response. Both CT corrected and uncorrected PET images showed hypermetabolism in the massively calcified lymph nodes in the neck, mediastinum, axilla and abdomen, indicative of active residual disease.
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