Isolated Bladder Condyloma in an Immunocompetent Female: Case Report and Literature Review

There are over 200 strains in the human papilloma virus (HPV) family, but there are four predominant infectious strains associated with symptoms and carcinomas: HPV 6 and HPV 11 cause approximately 90% of all genital warts, HPV 16 and HPV 18 are associated with anogenital carcinomas (1). Condyloma acuminata (CA), the warty lesions caused by HPV, are generally present on external genitalia and mucocutaneous junctions and can spread locally. There are rare reports of CA found in the urinary tract, but these are generally seen in patients who are immunocompromised and who have had a history of genital CA (2). While genital condylomas have been associated with increased risk of cervical, anogenital, penile, and head and neck cancers, their role in urothelial carcinoma has been very inconclusive, (3) with some reports suggesting an increased risk for progression to squamous cell carcinoma and need for close monitoring (4). We report a rare case of isolated bladder CA found in an immunocompetent female without a history of genital CA.