Retrospective Analysis of Postchemotheraphy Retroperitoneal Lymph Node Dissection (PC-RPLND) Results in Patients with Non-Seminomatous Testicular Cancers

Objective\udResection of residual masses after chemoteraphy in patients with nonseminomatous\udtesticular cancer is recommended. In our study, we evaluated\udthe patients’ data underwent post chemotherapy retroperitoneal lymph node\uddissection (PC-RPLND).\udMaterials and Methods\udPatients with advanced staged tumors and Non-seminomatous germ cells\udand having residual mass after chemotherapy whose tumor markers returned\udto normal were selected in the study. Pre-chemotherapy mass size, postchemoterapy\udmass size, decrease rate in the mass size, prognostic factors of\udlocal tumor, International Germ Cell Collaborative Clasification (IGCCC) risk\udgroups, and teratoma existence in primary pathology, PC-RPLND pathologies\udwere compared for fibrozis, teratoma or viable tumor presence. In addition,\udpatients with and without intraoperative complications were compared in\udterms of the same parameters. Comparisons were conducted using Statistical\udPackages for the Social Sciences (SPSS) 16.0 and p<0.05 was considered\udstatistically significantResults\udTwenty six patients were included in the study. Respectively 4 (15%) viable\udtumors, 14 (54%) teratoma, 8 (31%) necrosis were observed in patients\udafter PC-RPLND. No significant differences were observed in PC-RPLND\udpathology results in IGCCC risk groups depending on presence of teratoma\udin primary tumor or existence of more than 50% embryonal carcinoma after\udorchiectomy pathology. Teratoma in 6 of 8 patients with no decrease in the\udmass rate and viable tumor in 2 patients were detected. More than 90%\udreduction rate in the mass was detected in only one patient whose PC-RPLND\udpathology result was necrosis.There were no significant variations between\udcomplication developed and undeveloped patients in terms of mass size and\udlive tumor existence.\udConclusion\udOur data is consistent with the current literature. The mass size decrease\udrate, teratoma presence in orchiectomy material, IGCCC risk groups and local\udprognostic factors are not accurate predictive factors in determining the PCRPLND\udpatholog