Growth Hormone/Insulin-Like Growth Factor-1 Axis as Related to Body Mass Index in Patients with Idiopathic Short Stature | Zendy

Cengiz Pınar | Zendy; Baş Firdevs | Zendy; Fatmahan Atalar | Zendy; Ahmet Uçar | Zendy; Darendeliler Feyza | Zendy; Akan Gökçe | Zendy; Tarhan Tuğba | Zendy

Open Access

Growth Hormone/Insulin-Like Growth Factor-1 Axis as Related to Body Mass Index in Patients with Idiopathic Short Stature

Author(s) -

Cengiz Pınar,

Baş Firdevs,

Fatmahan Atalar,

Ahmet Uçar,

Darendeliler Feyza,

Akan Gökçe,

Tarhan Tuğba

Publication year - 2013

Publication title -

journal of clinical research in pediatric endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.566

H-Index - 35

eISSN - 1308-5735

pISSN - 1308-5727

DOI - 10.4274/jcrpe.901

Subject(s) - medicine , idiopathic short stature , endocrinology , body mass index , basal (medicine) , short stature , anthropometry , insulin like growth factor , growth factor , insulin , hormone , growth hormone , receptor

Idiopathic short stature (ISS) is a heterogeneous disorder. An impairment of growth hormone (GH)/insulin-like growth factor 1 (IGF-1)/IGF-1 receptor (IGF-1 R) axis is postulated. To evaluate the somatotropic axis in relation to body mass index (BMI), serum IGF-1, IGF-binding protein-3 (IGFBP-3) and the expression of IGF-1 R genes in patients with ISS.

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