Relationships Between Osteocalcin, Glucose Metabolism and Adiponectin in Obese Children: Is there Crosstalk Between Bone Tissue and Glucose Metabolism?
Author(s) -
Nilay Abseyi,
Zeynep Şıklar,
Merih Berberoğlu,
Bülent Hacıhamdioğlu,
Şenay Savaş Erdeve,
Gönül Öçal
Publication year - 2012
Publication title -
journal of clinical research in pediatric endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.566
H-Index - 35
eISSN - 1308-5735
pISSN - 1308-5727
DOI - 10.4274/jcrpe.831
Subject(s) - insulin resistance , osteocalcin , endocrinology , adiponectin , medicine , metabolic syndrome , dyslipidemia , insulin , carbohydrate metabolism , hyperinsulinemia , obesity , biology , biochemistry , alkaline phosphatase , enzyme
Recently, scientific interest has focused on the association between osteocalcin, which originates from the skeletal system, and glucose metabolism. Although the association between lipid metabolism, adiponectin, and metabolic syndrome is well known, that between obesity, insulin resistance, and osteocalcin have not been clarified yet in children. The aim of this study was to assess the prevalence of insulin resistance in obese children and adolescents, as well as to investigate the effects of adiponectin and osteocalcin on the development of metabolic syndrome and insulin resistance.
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