Role of Versican and ADAMTS-1 in Polycystic Ovary Syndrome | Zendy

Sibel Özler | Zendy; Efser Öztaş | Zendy; Aytekin Tokmak | Zendy; Merve Ergin | Zendy; Meryem Kuru Pekcan | Zendy; Başak Gümüş Güler | Zendy; Halil İbrahim Yakut | Zendy; Nafiye Yılmaz | Zendy

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Role of Versican and ADAMTS-1 in Polycystic Ovary Syndrome

Author(s) -

Sibel Özler,

Efser Öztaş,

Aytekin Tokmak,

Merve Ergin,

Meryem Kuru Pekcan,

Başak Gümüş Güler,

Halil İbrahim Yakut,

Nafiye Yılmaz

Publication year - 2016

Publication title -

journal of clinical research in pediatric endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.566

H-Index - 35

eISSN - 1308-5735

pISSN - 1308-5727

DOI - 10.4274/jcrpe.3414

Subject(s) - versican , polycystic ovary , medicine , adamts , endocrinology , pathogenesis , luteinizing hormone , thrombospondin , hormone , insulin resistance , metalloproteinase , insulin , matrix metalloproteinase , proteoglycan , anatomy , cartilage

ADAMTS-1 is a matrix metalloproteinase which cleaves versican in the cumulus oocyte complex under the effect of luteinizing hormone surge in the periovulatory period. Altered levels may have a role in the pathogenesis of polycystic ovary syndrome (PCOS). We aimed to determine the serum versican and ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin motif-1) levels in PCOS patients and compare the results with healthy controls.

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